Advanced Detection of Mycoplasmas

How Real-Time PCR Analysis Helps Save Time and Money for Biopharmaceutical Manufacturers

A white paper by Dennis Champagne, Director, Laboratory Services of Microtest Labs.

Contamination by mycoplasmal organisms is an ever-present concern in biopharmaceutical manufacturing. Their properties make them ready sources of contamination, while rendering them difficult and time-consuming to detect. This paper examines relevant mycoplasmal characteristics, as well as established testing solutions. It discusses the use of real-time PCR analysis as an alternative testing method for fast, preliminary mycoplasma detection. It also examines how this analysis is deployed by a cutting-edge laboratory to minimize testing delays and enable safe, high-volume biopharmaceutical production.

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